Learn Python with Talk Python's 270+ hours of courses

Talk Python To Me

A podcast on Python and related technologies


Latest episode:
#518 Celebrating Django's 20th Birthday With Its Creators

Twenty years after a scrappy newsroom team hacked together a framework to ship stories fast, Django remains the Python web framework that ships real apps, responsibly. In this anniversary roundtable with its creators and long-time stewards: Simon Willison, Adrian Holovaty, Will Vincent, Jeff Triplett, and Thibaud Colas, we trace the path from the Lawrence Journal-World to 1.0, DjangoCon, and the DSF; unpack how a BSD license and a culture of docs, tests, and mentorship grew a global community; and revisit lessons from deployments like Instagram. We talk modern Django too: ASGI and async, HTMX-friendly patterns, building APIs with DRF and Django Ninja, and how Django pairs with React and serverless without losing its batteries-included soul. You’ll hear about Django Girls, Djangonauts, and the Django Fellowship that keep momentum going, plus where Django fits in today’s AI stacks. Finally, we look ahead at the next decade of speed, security, and sustainability.
Full details »

Thibaud Colas
Thibaud Colas
Adrian Holovaty
Adrian Holovaty
Jeff Triplet
Jeff Triplet
Simon Willison
Simon Willison
William Vincent
William Vincent

Take Python to the next level with our online courses

Upcoming episodes

Panelists
Panelists
(up next)
Data Science Cloud Lessons at Scale

Today on Talk Python: What really happens when your data work outgrows your laptop. Matthew Rocklin, creator of Dask and cofounder of Coiled, and Nat Tabris a staff software engineer at Coiled join me to unpack the messy truth of cloud-scale Python. During the episode we actually spin up a 2,000 core cluster from a notebook, twice! We also discuss picking between pandas and Polars, when GPUs help, and how to avoid surprise bills. Real lessons, real tradeoffs, shared by people who have built this stuff. Stick around.

Panelists
Panelists
(and then)
Red Teaming LLMs and GenAI with PyRIT

English is now an API. Our apps read untrusted text; they follow instructions hidden in plain sight, and sometimes they turn that text into action. If you connect a model to tools or let it read documents from the wild, you have created a brand new attack surface. In this episode, we will make that concrete. We will talk about the attacks teams are seeing in 2025, the defenses that actually work, and how to test those defenses the same way we test code. Our guides are Tori Westerhoff and Roman Lutz from Microsoft. They help lead AI red teaming and build PyRIT, a Python framework the Microsoft AI Red Team uses to pressure test real products. By the end of this hour you will know where the biggest risks live, what you can ship this quarter to reduce them, and how PyRIT can turn security from a one time audit into an everyday engineering practice.

Khuyen Tran
Khuyen Tran
(finally)
Data Sci Tips and Tricks from CodeCut.ai

What listeners think

Awesome Python Goodness
This is the podcast that got me into listening to nearly only technical ones. All the episodes are fun and informative, and I can't recommend it enough for every Pythonista (and others).
-- Nikola Kantar
I just started learning Python and this is perfect!!!
Thankfully we live in the age where you have a podcast for everything. I just started learning programming and Python is my first language. I LOVE THE INTRO SONG!
-- Ruben005
Great addition
Finally, a great python podcast. Highly informative.
-- JueJung
Do you love the show and want to tell the world?
Send us a review or post one on iTunes. Thanks!

Python Bytes Podcast

Do you enjoy Talk Python To Me? We created a second podcast to be the perfect counterpart to the long-form interview format on Talk Python:

Python Bytes:
Python headlines delivered directly to your earbuds


If you are looking for a 15 minute conversation on the topical items of the week in the Python ecosystem, be sure to jump over to Python Bytes and subscribe.
Python Bytes Podcast

Talk Python Merchandise

Support the show and share your Python pride with the Talk Python To Me T-shirt. .


Talk Python To Me T-Shirt

More about Talk Python to Me

Talk Python to Me is a weekly podcast hosted by Michael Kennedy. The show covers a wide array of Python topics as well as many related topics.

The format is a casual 1-hour conversation with industry experts.

Have feedback for the show? Send it to contact@talkpython.fm. We'd love to hear from you.

Michael Kennedy
Your host
Michael Kennedy

Suggest a show or guest

We are always on the look out for exciting topics to bring to you on Talk Python To Me. We could use your help!

Do you have a great idea for a show? Do know a dynamic Python personality who we should be speaking to? Send us an email!


Suggest a podcast guest
Talk Python's Mastodon Michael Kennedy's Mastodon