Today we’re digging into the Model Context Protocol, or MCP. Think LSP for AI: build a small Python service once and your tools and data show up across editors and agents like VS Code, Claude Code, and more. My guest, Den Delimarsky from Microsoft, helps build this space and will keep us honest about what’s solid versus what's just shiny. We’ll keep it practical: transports that actually work, guardrails you can trust, and a tiny server you could ship this week. By the end, you’ll have a clear mental model and a path to plug Python into the internet of agents.
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A lot of people building software today never took the traditional CS path. They arrived through curiosity, a job that needed automating, or a late-night itch to make something work. This week, David Kopec joins me to talk about rebuilding computer science for exactly those folks, the ones who learned to program first and are now ready to understand the deeper ideas that power the tools they use every day.
In this episode, I’m talking with Vincent Warmerdam about treating LLMs as just another API in your Python app, with clear boundaries, small focused endpoints, and good monitoring. We’ll dig into patterns for wrapping these calls, caching and inspecting responses, and deciding where an LLM API actually earns its keep in your architecture.
For years, building interactive widgets in Python notebooks meant wrestling with toolchains, platform quirks, and a mountain of JavaScript machinery. Most developers took one look and backed away slowly. Trevor Manz decided that barrier did not need to exist. His idea was simple: give Python users just enough JavaScript to unlock the web’s interactivity, without dragging along the rest of the web ecosystem. That idea became anywidget, and it is quickly becoming the quiet connective tissue of modern interactive computing. Today we dig into how it works, why it has taken off, and how it might change the way we explore data.
Educational and enjoyableA great podcast that keeps me motivated to learn and grow in the Python community.
AmazingI have learned so much because of this podcast!
Favorite podcast ever!Seriously.
Talk Python to Me is a weekly podcast hosted by
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The show covers a wide array of Python topics as well as
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The format is a casual 1-hour conversation with industry
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