New course: Agentic AI for Python Devs

Talk Python To Me

A podcast on Python and related technologies


#1
Python Podcast
10+
Years Running
49M+
Downloads

Latest episode: #531 Talk Python in Production

Have you ever thought about getting your small product into production, but are worried about the cost of the big cloud providers? Or maybe you think your current cloud service is over-architected and costing you too much? Well, in this episode, we interview Michael Kennedy, author of "Talk Python in Production," a new book that guides you through deploying web apps at scale with right-sized engineering.

Upcoming episodes

Panelists
Panelists
(up next)
2025 Python Year in Review

Python in 2025 is in a delightfully refreshing place: the GIL's days are numbered, packaging is getting sharper tools, and the type checkers are multiplying like gremlins snacking after midnight. On this episode, we have an amazing panel to give us a range of perspectives on what matter in 2025 in Python. We have Barry Warsaw, Brett Cannon, Gregory Kapfhammer, Jodie Burchell, Reuven Lerner, and Thomas Wouters on to give us their thoughts.

Panelists
Panelists
(and then)
Web Frameworks in Prod by Their Creators

Today on Talk Python, the creators behind FastAPI, Flask, Django, Quart, and Litestar get practical about running apps based on their framework in production. Deployment patterns, async gotchas, servers, scaling, and the stuff you only learn at 2 a.m. when the pager goes off. For Django, we have Carlton Gibson and Jeff Triplet. For Flask, we have David Lord and Phil Jones, and on team Litestar we have Janek Nouvertné and Cody Fincher, and finally Sebastián Ramírez from FastAPI is here. Let’s jump in.

Vincent D. Warmerdam
Vincent D. Warmerdam
(finally)
diskcache: Your secret Python perf weapon

Your cloud SSD is sitting there, bored, and it would like a job. Today we’re putting it to work with DiskCache, a simple, practical cache built on SQLite that can speed things up without spinning up Redis or extra services. Once you start to see what it can do, a universe of possibilities opens up. We're joined by Vincent Warmerdam to dive into DiskCache.

Stay connected with Talk Python

Listen for Free

Add Talk Python to your favorite podcast player and never miss an episode.

Subscribe Now

Join the Newsletter

Get episode updates, Python news, and exclusive content delivered to your inbox.

Subscribe to Newsletter

Talk Python changed my career

From career changes to breakthrough moments, hear how the podcast has made a real impact.

"The podcast has been a wealth of information and has positively contributed to my efforts to learn Python. Frankly, the podcast is the best way I've found to augment the training videos, documentation, and books I've used to learn the language."
— Dennis M.
"This is the podcast that got me into listening to nearly only technical ones. All the episodes are fun and informative, and I can't recommend it enough for every Pythonista."
— Nikola Kantar
"Each and every episode, I learn at least one thing that motivates me to change my day to day life."
— Ronak15

Feedback on the show

Great Python Podcast
Talk Python To Me is in the rotation of podcasts that I listen to on a regular basis. The guests are always interesting. The topics are quite often relevant to things I'm working on or thinking about. Michael, the host, also keeps things moving at a good pace and keeps the conversation lively. I also enjoy his "regular questions" at the end of the show. Always good to hear how other folks answer those questions!
— writes_on
Exceptional for those new to Python
The podcast has been a wealth of information and has positively contributed to my efforts to learn Python. Michael interviews a great cross-section of people using Python. The biggest benefit for me has been the exposure to the various libraries and seeing the multitude of areas that I can use Python. Frankly, the podcast this the best way I've found to augment the training videos, documentation, and books I've used to learn the language.
— Dennis M.
Informative, addictive, and powerful!
I have been following this podcast since awhile now and I have to say that Michael does a great job picking topics which listeners relate to and all the information is very much helpful for a person who is getting their feet wet in Python or an experienced developer. Each and every episode, I learn at least one thing that motivates me to change my day to day life. I am looking for more Python stuff and I would love Michael to continue with the same speed as he is going. Highly recommended for all Pythonistas.
— Ronak15
Do you love the show and want to tell the world? Send us a review or post one on iTunes. Thanks!

Take Python to the next level

Online courses from Talk Python. Real courses with real coding helping you build production-ready skills.

Training for teams

Looking to level up your entire team's Python skills? Talk Python Training offers bulk discounts for organizations, plus an admin dashboard to track team progress and completion.

Learn about team plans
Talk Python for Production book cover by Michael Kennedy

From the creator of Talk Python

Python for Production

Learn how to build, deploy, and scale production-ready Python applications. From best practices to real-world patterns, this book covers everything you need to take your Python projects from prototype to production.

Wondering if we cover a topic?

Search across 533+ episodes to find exactly what you're looking for.

Search episodes

Python Bytes Podcast

Do you enjoy Talk Python To Me? We created a second podcast to be the perfect counterpart to the long-form interview format.

Python Bytes delivers Python headlines directly to your earbuds in just 15-20 minutes per week. The topical items of the Python ecosystem, condensed and ready to go.

Michael Kennedy
Michael Kennedy
Your Host

About the Show

Talk Python to Me is a weekly podcast covering a wide array of Python topics as well as many related technologies. Each episode features a casual 1-hour conversation with industry experts.

Have feedback for the show? We'd love to hear from you.

Suggest a podcast guest

Suggest a show or guest

We are always on the look out for exciting topics to bring to you on Talk Python To Me. Do you have a great idea for a show? Know a dynamic Python personality who we should be speaking to?

Ready to learn from the best minds in Python?

Talk Python's Mastodon Michael Kennedy's Mastodon